Phytochemicals of Periploca aphylla Dcne. ameliorated streptozotocin-induced diabetes in rat
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Hypoglycemic effect of Polygonatum orientale Desf. rhizome extract on diabetes induced by streptozotocin in rat model
Background: Polygonatum orientale, an herbaceous and perennial plant from family Asparagaceae, is native to the forests of northern Iran. The hypoglycemic effects of other species of the Polygonatum have been proven. Objective: The aim of this study was to evaluate the hypoglycemic effect of P. orientale rhizome extract and its effects on the antioxidant enzymes in the plasma of the normal and ...
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Background and objectives: Melissa officinalis (MO) has shown antioxidant and anti-inflammatory properties and is traditionally believed to have anti-hyperglycemic effects. This study aims to evaluate the protective effects of MO on streptozotocin (STZ) induced pancreatic damage and thereupon diabetes in rats. Methods: STZ (60 mg/kg) was injected intraperitoneally to the rats in order to induc...
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It has been previously shown that dextran sulfate administered to diabetic rats accumulates in the liver and kidney, and this could be due to a malfunction of the lysosomal digestive pathway. The aim of the present study was to evaluate the expression and activities of lysosomal enzymes that act upon proteins and sulfated polysaccharides in the livers of diabetic rats. Diabetes mellitus was ind...
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Background and Objective: Teucrium polium (TP) has shown hypoglycemic effect in type 1 diabetes induced by single high dose of the cytotoxic agent streptozotocin (STZ) in rats. This study was conducted to evaluate whether its aqueous extract could have such an effect in multiple low-dose STZ-induced model of type 1 diabetes in rats. Materials and Methods: Male Wistar rats were divided into cont...
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ژورنال
عنوان ژورنال: Environmental Health and Preventive Medicine
سال: 2021
ISSN: 1342-078X,1347-4715
DOI: 10.1186/s12199-021-00962-0